GBX2

GBX2
Identifiers
Aliases	GBX2, gastrulation brain homeobox 2
External IDs	OMIM: 601135; MGI: 95668; HomoloGene: 1138; GeneCards: GBX2; OMA:GBX2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	236,168,386 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	89,858,901 bp
RNA expression pattern
	Top expressed in
	gonad; ; testicle; ; putamen; ; stromal cell of endometrium; ; caudate nucleus; ; C1 segment; ; Hypothalamus; ; nucleus accumbens; ; substantia nigra; ; right hemisphere of cerebellum;
	Top expressed in
	zygote; ; primary oocyte; ; medial dorsal nucleus; ; tail of embryo; ; primitive streak; ; secondary oocyte; ; medial geniculate nucleus; ; otic vesicle; ; embryo; ; lumbar subsegment of spinal cord;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity; RNA polymerase II core promoter sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; transcription factor binding;
Cellular component	nucleus;
Biological process	autonomic nervous system development; midbrain-hindbrain boundary morphogenesis; regulation of transcription, DNA-templated; thalamus development; hindbrain development; transcription by RNA polymerase II; tube morphogenesis; transcription, DNA-templated; nervous system development; cerebellum development; cerebellar granule cell precursor proliferation; axon guidance; forebrain neuron development; midbrain-hindbrain boundary development; rhombomere 2 development; inner ear morphogenesis; neural crest cell migration; branching involved in blood vessel morphogenesis; cell population proliferation; positive regulation of transcription by RNA polymerase II; regulation of nervous system development;
	Sources:Amigo / QuickGO
Orthologs
	2637
	14472
	ENSG00000168505
	ENSMUSG00000034486
	P52951
	P48031
	NM_001485; NM_001301687
	NM_010262
	NP_001288616; NP_001476
	NP_034392
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein GBX-2 is a protein that in humans is encoded by the GBX2 gene.