GCC2

GCC2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3BBP
Identifiers
Aliases	GCC2, GCC185, RANBP2L4, REN53, GRIP and coiled-coil domain containing 2
External IDs	OMIM: 612711; MGI: 1917547; HomoloGene: 45639; GeneCards: GCC2; OMA:GCC2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	108,509,415 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; corpus epididymis; ; testicle; ; epithelium of colon; ; bronchial epithelial cell; ; jejunal mucosa; ; Epithelium of choroid plexus; ; caput epididymis; ; Brodmann area 23; ; endothelial cell;
	n/a
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; identical protein binding;
Cellular component	cytoplasm; trans-Golgi network; Golgi apparatus; membrane; cytosol; nucleoplasm;
Biological process	Golgi to plasma membrane protein transport; protein transport; microtubule anchoring; protein targeting to lysosome; retrograde transport, endosome to Golgi; late endosome to Golgi transport; regulation of protein exit from endoplasmic reticulum; microtubule organizing center organization; recycling endosome to Golgi transport; Golgi ribbon formation; protein localization to Golgi apparatus; transport;
	Sources:Amigo / QuickGO
Orthologs
	9648
	70297
	ENSG00000135968
	ENSMUSG00000038039
	Q8IWJ2
	Q8CHG3
	NM_181453
	NM_027375
	NP_852118
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

GRIP and coiled-coil domain-containing protein 2 is a protein that in humans is encoded by the GCC2 gene.

The protein encoded by this gene is a peripheral membrane protein localized to the trans-Golgi network. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.