KAT2A

KAT2A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1F68, 1Z4R, 3D7C, 5H86, 5H84
Identifiers
Aliases	KAT2A, GCN5, GCN5L2, PCAF-b, hGCN5, lysine acetyltransferase 2A
External IDs	OMIM: 602301; MGI: 1343101; HomoloGene: 41343; GeneCards: KAT2A; OMA:KAT2A - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	42,121,367 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	100,603,291 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; left ovary; ; right ovary; ; right hemisphere of cerebellum; ; right adrenal cortex; ; right frontal lobe; ; left uterine tube; ; left adrenal cortex; ; body of uterus; ; canal of the cervix;
	Top expressed in
	internal carotid artery; ; external carotid artery; ; otic placode; ; tail of embryo; ; otic vesicle; ; saccule; ; genital tubercle; ; epiblast; ; lacrimal gland; ; hair follicle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; transcription coactivator activity; N-acetyltransferase activity; transcription factor binding; histone deacetylase binding; chromatin binding; H3 histone acetyltransferase activity; protein binding; acetyltransferase activity; histone acetyltransferase activity (H4-K12 specific); protein phosphatase binding; acyltransferase activity; histone acetyltransferase activity; thiol-dependent deubiquitinase; peptide-lysine-N-acetyltransferase activity; histone succinyltransferase activity;
Cellular component	transcription factor TFTC complex; nucleoplasm; histone acetyltransferase complex; mitotic spindle; extracellular space; nucleus; chromosome; cytoplasm; centrosome; microtubule organizing center; cytoskeleton; oxoglutarate dehydrogenase complex;
Biological process	positive regulation of transcription regulatory region DNA binding; somitogenesis; epigenetic maintenance of chromatin in transcription-competent conformation; chromatin remodeling; metencephalon development; cellular response to nerve growth factor stimulus; regulation of transcription, DNA-templated; regulation of protein stability; response to organic cyclic compound; multicellular organism growth; positive regulation of protein targeting to mitochondrion; regulation of transcription by RNA polymerase II; cardiac muscle cell differentiation; cellular response to tumor necrosis factor; histone H3-K14 acetylation; positive regulation of cell projection organization; in utero embryonic development; transcription by RNA polymerase II; transcription, DNA-templated; nervous system development; positive regulation of histone acetylation; histone deubiquitination; telencephalon development; neural tube closure; response to nutrient levels; regulation of autophagy of mitochondrion; histone acetylation; histone H3 acetylation; cell population proliferation; viral process; intracellular distribution of mitochondria; histone H4-K12 acetylation; alpha-tubulin acetylation; midbrain development; protein deubiquitination; cytokine production; heart development; long-term memory; internal peptidyl-lysine acetylation; regulation of regulatory T cell differentiation; positive regulation of transcription by RNA polymerase II; negative regulation of centriole replication; regulation of synaptic plasticity; regulation of T cell activation; limb development; histone succinylation; positive regulation of cardiac muscle cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	2648
	14534
	ENSG00000108773
	ENSMUSG00000020918
	Q92830
	Q9JHD2
	NM_021078; NM_001376227
	NM_001038010; NM_020004
	NP_066564; NP_001363156
	NP_001033099; NP_064388
	Wikidata
View/Edit Human	View/Edit Mouse

Histone acetyltransferase KAT2A is an enzyme that in humans is encoded by the KAT2A gene.