GCNT1

GCNT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2GAK, 2GAM, 3OTK
Identifiers
Aliases	GCNT1, C2GNT, C2GNT-L, C2GNT1, G6NT, NACGT2, NAGCT2, glucosaminyl (N-acetyl) transferase 1, core 2, glucosaminyl (N-acetyl) transferase 1
External IDs	OMIM: 600391; MGI: 95676; HomoloGene: 37486; GeneCards: GCNT1; OMA:GCNT1 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	76,651,203 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	17,350,208 bp
RNA expression pattern
	Top expressed in
	duodenum; ; jejunal mucosa; ; islet of Langerhans; ; amniotic fluid; ; Achilles tendon; ; mucosa of sigmoid colon; ; secondary oocyte; ; rectum; ; mucosa of ileum; ; monocyte;
	Top expressed in
	right kidney; ; parotid gland; ; proximal tubule; ; granulocyte; ; human kidney; ; stroma of bone marrow; ; atrioventricular valve; ; left colon; ; mesenteric lymph nodes; ; aortic valve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; acetylglucosaminyltransferase activity; glycosyltransferase activity; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity; protein binding;
Cellular component	integral component of membrane; Golgi apparatus; membrane; Golgi cisterna; trans-Golgi network; Golgi membrane; extracellular space;
Biological process	glycoprotein biosynthetic process; tissue morphogenesis; response to insulin; protein glycosylation; kidney morphogenesis; O-glycan processing; leukocyte tethering or rolling; cell adhesion molecule production;
	Sources:Amigo / QuickGO
Orthologs
	2650
	14537
	ENSG00000187210
	ENSMUSG00000038843
	Q02742
	Q09324
	NM_001097633; NM_001097634; NM_001097635; NM_001097636; NM_001490
	NM_001136484; NM_010265; NM_173442
	NP_001091102; NP_001091103; NP_001091104; NP_001091105; NP_001481
	NP_001129956; NP_034395; NP_775618
	Wikidata
View/Edit Human	View/Edit Mouse

Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase is an enzyme that in humans is encoded by the GCNT1 gene.

This gene is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified.