GDAP1

GDAP1
Identifiers
Aliases	GDAP1, CMT4, CMT4A, CMTRIA, ganglioside induced differentiation associated protein 1
External IDs	OMIM: 606598; MGI: 1338002; HomoloGene: 40713; GeneCards: GDAP1; OMA:GDAP1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	74,518,007 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	17,234,495 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; secondary oocyte; ; Brodmann area 23; ; cerebellar vermis; ; postcentral gyrus; ; entorhinal cortex; ; Pons; ; middle temporal gyrus; ; pars compacta; ; superior frontal gyrus;
	Top expressed in
	barrel cortex; ; substantia nigra; ; zygote; ; ventral tegmental area; ; medial vestibular nucleus; ; pontine nuclei; ; secondary oocyte; ; dorsal tegmental nucleus; ; habenula; ; primary oocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	glutathione transferase activity;
Cellular component	integral component of membrane; mitochondrial outer membrane; integral component of mitochondrial outer membrane; membrane; mitochondrion; nucleus; cytoplasm; cytosol;
Biological process	mitochondrial fusion; protein targeting to mitochondrion; response to retinoic acid; mitochondrial fission; cellular response to vitamin D; glutathione metabolic process; mitochondrion organization;
	Sources:Amigo / QuickGO
Orthologs
	54332
	14545
	ENSG00000104381
	ENSMUSG00000025777
	Q8TB36
	O88741
NM_001040875; NM_018972; NM_001362929; NM_001362930; NM_001362931;
	NM_001362932
	NM_010267
NP_001035808; NP_061845; NP_001349858; NP_001349859; NP_001349860;
	NP_001349861
	NP_034397
	Wikidata
View/Edit Human	View/Edit Mouse

Ganglioside-induced differentiation-associated protein 1 is a type of protein that in humans is encoded by the GDAP1 gene.

This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms have been identified for this gene.