GFER

GFER
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3MBG, 3O55, 3TK0, 3U2L, 3U2M, 3U5S, 4LDK
Identifiers
Aliases	GFER, ALR, ERV1, HERV1, HPO, HPO1, HPO2, HSS, growth factor, augmenter of liver regeneration, MMCHD, MPMCD
External IDs	OMIM: 600924; MGI: 107757; HomoloGene: 55884; GeneCards: GFER; OMA:GFER - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	1,987,749 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	24,915,130 bp
RNA expression pattern
	Top expressed in
	vena cava; ; mucosa of transverse colon; ; body of pancreas; ; muscle of thigh; ; olfactory zone of nasal mucosa; ; granulocyte; ; body of tongue; ; right lobe of liver; ; right testis; ; gastrocnemius muscle;
	Top expressed in
	seminiferous tubule; ; primary oocyte; ; Ileal epithelium; ; left lobe of liver; ; Paneth cell; ; triceps brachii muscle; ; embryo; ; proximal tubule; ; epiblast; ; right kidney;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein-disulfide reductase activity; oxidoreductase activity; growth factor activity; protein binding; thiol oxidase activity; flavin adenine dinucleotide binding; flavin-linked sulfhydryl oxidase activity;
Cellular component	extracellular region; mitochondrial intermembrane space; cytoplasm; mitochondrion; cytosol;
Biological process	liver development; regulation of signaling receptor activity; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	2671
	11692
	ENSG00000127554
	ENSMUSG00000040888
	P55789
	P56213
	NM_005262
	NM_023040; NM_212443; NM_001379038; NM_001379039
	NP_005253
	NP_075527
	Wikidata
View/Edit Human	View/Edit Mouse

Growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae), also known as GFER, or Hepatopoietin is a protein which in humans is encoded by the GFER gene. This gene is also known as essential for respiration and vegatative growth, augmenter of liver regeneration, and growth factor of Erv1-like/Hepatic regenerative stimulation substance.