GFRA1

GFRA1
Identifiers
Aliases	GFRA1, GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1, GDNF family receptor alpha 1
External IDs	OMIM: 601496; MGI: 1100842; HomoloGene: 3855; GeneCards: GFRA1; OMA:GFRA1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	116,273,467 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	58,444,341 bp
RNA expression pattern
	Top expressed in
	trigeminal ganglion; ; spinal ganglia; ; pars reticulata; ; parietal pleura; ; corpus epididymis; ; lactiferous duct; ; pars compacta; ; nipple; ; left uterine tube; ; cardia;
	Top expressed in
	vestibular membrane of cochlear duct; ; habenula; ; facial motor nucleus; ; dentate gyrus of hippocampal formation granule cell; ; left lobe of liver; ; lateral septal nucleus; ; iris; ; medullary collecting duct; ; ciliary body; ; substantia nigra;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signaling receptor binding; glial cell-derived neurotrophic factor receptor activity; signaling receptor activity;
Cellular component	anchored component of membrane; extracellular exosome; membrane; extrinsic component of membrane; intracellular anatomical structure; plasma membrane; external side of plasma membrane; receptor complex;
Biological process	cell surface receptor signaling pathway; nervous system development; MAPK cascade; glial cell-derived neurotrophic factor receptor signaling pathway; axon guidance; regulation of molecular function;
	Sources:Amigo / QuickGO
Orthologs
	2674
	14585
	ENSG00000151892
	ENSMUSG00000025089
	P56159
	P97785
NM_001145453; NM_005264; NM_145793; NM_001348096; NM_001348098;
	NM_001348099
	NM_001285457; NM_010279
NP_001138925; NP_005255; NP_665736; NP_001335025; NP_001335027;
	NP_001335028; NP_001369485; NP_001369486; NP_001369487; NP_001369488; NP_001369489; NP_001369490
	NP_001272386; NP_034409
	Wikidata
View/Edit Human	View/Edit Mouse

GDNF family receptor alpha-1 (GFRα1), also known as the GDNF receptor, is a protein that in humans is encoded by the GFRA1 gene.