GFRA2 (gene)

GFRA2
Identifiers
Aliases	GFRA2, GDNFRB, NRTNR-ALPHA, NTNRA, RETL2, TRNR2, GDNF family receptor alpha 2
External IDs	OMIM: 601956; MGI: 1195462; HomoloGene: 1145; GeneCards: GFRA2; OMA:GFRA2 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	21,812,357 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	71,217,278 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; Brodmann area 10; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; right frontal lobe; ; Brodmann area 9; ; primary visual cortex; ; cingulate gyrus; ; anterior cingulate cortex; ; testicle;
	Top expressed in
	left lung lobe; ; median eminence; ; lumbar spinal ganglion; ; ascending aorta; ; aortic valve; ; lateral septal nucleus; ; genital tubercle; ; Gonadal ridge; ; molar; ; arcuate nucleus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	glial cell-derived neurotrophic factor receptor activity; signaling receptor activity;
Cellular component	anchored component of membrane; membrane; extrinsic component of membrane; plasma membrane; intracellular anatomical structure; external side of plasma membrane; receptor complex;
Biological process	glial cell-derived neurotrophic factor receptor signaling pathway; nervous system development; transmembrane receptor protein tyrosine kinase signaling pathway; MAPK cascade; axon guidance; positive regulation of peptidyl-serine phosphorylation of STAT protein; negative regulation of protein autophosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	2675
	14586
	ENSG00000168546
	ENSMUSG00000022103
	O00451
	O08842
	NM_001165038; NM_001165039; NM_001495
	NM_008115; NM_001302094; NM_001302095
	NP_001158510; NP_001158511; NP_001486
	NP_001289023; NP_001289024; NP_032141
	Wikidata
View/Edit Human	View/Edit Mouse

GDNF family receptor alpha-2 (GFRα2), also known as the neurturin receptor, is a protein that in humans is encoded by the GFRA2 gene.