Growth hormone–releasing hormone
| Growth hormone releasing hormone | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | GHRH | ||||||
| Alt. symbols | GRF, GHRF | ||||||
| CAS number | |||||||
| NCBI gene | 2691 | ||||||
| HGNC | 4265 | ||||||
| OMIM | 139190 | ||||||
| RefSeq | NM_021081 | ||||||
| UniProt | P01286 | ||||||
| Other data | |||||||
| Locus | Chr. 20 p12 or q11.2-q12 | ||||||
| |||||||
Growth hormone–releasing hormone (GHRH), also known as somatocrinin among other names in its endogenous form and as somatorelin (INN) in its pharmaceutical form, is a releasing hormone of growth hormone (GH). It is a 44-amino acid peptide hormone produced in the arcuate nucleus of the hypothalamus.
GHRH first appears in the human hypothalamus between 18 and 29 weeks of gestation, which corresponds to the start of production of growth hormone and other somatotropes in fetuses.