GJA4

GJA4
Identifiers
Aliases	GJA4, CX37, gap junction protein alpha 4
External IDs	OMIM: 121012; MGI: 95715; HomoloGene: 1556; GeneCards: GJA4; OMA:GJA4 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	34,795,747 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	127,207,832 bp
RNA expression pattern
	Top expressed in
	tibial arteries; ; apex of heart; ; right lung; ; vena cava; ; left ventricle; ; left coronary artery; ; right lobe of thyroid gland; ; right coronary artery; ; subcutaneous adipose tissue; ; right ventricle;
	Top expressed in
	primary oocyte; ; morula; ; external carotid artery; ; internal carotid artery; ; secondary oocyte; ; zygote; ; right lung; ; right lung lobe; ; left lung; ; ankle joint;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; gap junction; cell junction; plasma membrane; integral component of plasma membrane; connexin complex; membrane;
Biological process	cell communication; cell-cell signaling; blood vessel development; response to pain; calcium ion transport; cell-cell junction assembly; endothelium development;
	Sources:Amigo / QuickGO
Orthologs
	2701
	14612
	ENSG00000187513
	ENSMUSG00000050234
	P35212
	P28235
	NM_002060
	NM_008120
	NP_002051
	NP_032146
	Wikidata
View/Edit Human	View/Edit Mouse

Gap junction alpha-4 protein, also known as Connexin-37 or Cx37, is a protein that in humans is encoded by the GJA4 gene. This protein, like other Connexin proteins, forms connections between cells known as gap junctions. Connexin 37 can be found in many tissues including the ovary, heart, and kidney.