GJC2

GJC2
Identifiers
Aliases	GJC2, CX46.6, Cx47, GJA12, HLD2, LMPH1C, PMLDAR, SPG44, gap junction protein gamma 2, LMPHM3
External IDs	OMIM: 608803; MGI: 2153060; HomoloGene: 10715; GeneCards: GJC2; OMA:GJC2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	228,159,826 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	59,074,039 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; inferior ganglion of vagus nerve; ; subthalamic nucleus; ; ventral tegmental area; ; gonad; ; Pons; ; Medulla Oblongata; ; Brodmann area 10; ; lateral nuclear group of thalamus; ; pars compacta;
	Top expressed in
	lumbar subsegment of spinal cord; ; layer of hippocampus; ; deep cerebellar nuclei; ; radiate layer of hippocampus; ; molecular layer of neocortex; ; pontine nuclei; ; lateral geniculate nucleus; ; pyramidal layer of hippocampus; ; central gray substance of midbrain; ; globus pallidus;
	More reference expression data
	n/a
Gene ontology
Molecular function	gap junction channel activity; gap junction channel activity involved in cell communication by electrical coupling;
Cellular component	integral component of membrane; myelin sheath; cell junction; plasma membrane; connexin complex; membrane; gap junction; paranode region of axon; soma; perikaryon; proximal neuron projection;
Biological process	cell communication; cell-cell signaling; response to toxic substance; transmembrane transport; cell communication by electrical coupling; regulation of protein phosphorylation; brain development; positive regulation of gene expression; positive regulation of oligodendrocyte progenitor proliferation; positive regulation of calcium ion transmembrane transport; negative regulation of G1/S transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	57165
	118454
	ENSG00000198835
	ENSMUSG00000043448
	Q5T442
	Q8BQU6
	NM_020435
	NM_080454; NM_175452
	NP_065168
	NP_536702; NP_780661
	Wikidata
View/Edit Human	View/Edit Mouse

Gap junction gamma-2 (GJC2), also known as connexin-46.6 (Cx46.6) and connexin-47 (Cx47) and gap junction alpha-12 (GJA12), is a protein that in humans is encoded by the GJC2 gene.