GM2A

GM2A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1G13, 1PU5, 1PUB, 1TJJ, 2AF9, 2AG2, 2AG4, 2AG9
Identifiers
Aliases	GM2A, GM2-AP, SAP-3, GM2 ganglioside activator, GM2AP, ganglioside GM2 activator
External IDs	OMIM: 613109; MGI: 95762; HomoloGene: 349; GeneCards: GM2A; OMA:GM2A - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	151,270,440 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	55,003,855 bp
RNA expression pattern
	Top expressed in
	vulva; ; human penis; ; placenta; ; cervix epithelium; ; gums; ; gingival epithelium; ; skin of thigh; ; nipple; ; skin of hip; ; inferior ganglion of vagus nerve;
	Top expressed in
	gastrula; ; superior surface of tongue; ; mesenteric lymph nodes; ; ascending aorta; ; aortic valve; ; choroid plexus of fourth ventricle; ; gallbladder; ; vestibular membrane of cochlear duct; ; cumulus cell; ; adrenal gland;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	lipid transporter activity; phospholipase activator activity; beta-N-acetylgalactosaminidase activity; beta-N-acetylhexosaminidase activity; enzyme activator activity; hydrolase activity; sphingolipid activator protein activity;
Cellular component	cytoplasm; apical cortex; lysosomal lumen; mitochondrion; potassium:proton exchanging ATPase complex; cytoplasmic side of plasma membrane; lysosome; extracellular exosome; extracellular region; azurophil granule lumen; basolateral plasma membrane; apical plasma membrane;
Biological process	positive regulation of hydrolase activity; lipid transport; glycosphingolipid metabolic process; neuromuscular process controlling balance; lipid metabolism; lipid storage; nervous system process; learning or memory; oligosaccharide catabolic process; ganglioside metabolic process; ganglioside catabolic process; sphingolipid metabolic process; neutrophil degranulation; positive regulation of catalytic activity;
	Sources:Amigo / QuickGO
Orthologs
	2760
	14667
	ENSG00000196743
	ENSMUSG00000000594
	P17900
	Q60648
	NM_001167607; NM_000405
	NM_010299
	NP_000396; NP_001161079
	NP_034429
	Wikidata
View/Edit Human	View/Edit Mouse

GM2 ganglioside activator also known as GM2A is a protein which in humans is encoded by the GM2A gene.