GMEB2

GMEB2
Identifiers
Aliases	GMEB2, P79PIF, PIF79, GMEB-2, glucocorticoid modulatory element binding protein 2
External IDs	OMIM: 607451; MGI: 2652836; HomoloGene: 8228; GeneCards: GMEB2; OMA:GMEB2 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	63,627,101 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	180,929,828 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; buccal mucosa cell; ; thymus; ; mucosa of urinary bladder; ; mucosa of ileum; ; pancreatic ductal cell; ; granulocyte; ; right lobe of thyroid gland; ; tibialis anterior muscle; ; blood;
	Top expressed in
	granulocyte; ; hand; ; otolith organ; ; utricle; ; cumulus cell; ; blood; ; medial ganglionic eminence; ; neural layer of retina; ; thymus; ; bone marrow;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; transcription coactivator activity; metal ion binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm; cytoplasm; cytosol;
Biological process	regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of nucleic acid-templated transcription;
	Sources:Amigo / QuickGO
Orthologs
	26205
	229004
	ENSG00000101216
	ENSMUSG00000038705
	Q9UKD1
	P58929
	NM_012384
	NM_198169
	NP_036516
	NP_937812
	Wikidata
View/Edit Human	View/Edit Mouse

Glucocorticoid modulatory element-binding protein 2 is a protein that in humans is encoded by the GMEB2 gene.

This gene is a member of KDWK gene family. The product of this gene associates with GMEB1 protein, and the complex is essential for parvovirus DNA replication. Study of rat homolog implicates the role of this gene in modulation of transactivation by the glucocorticoid receptor bound to glucocorticoid response elements. This gene appears to use multiple polyadenylation sites.