Glypican 1

GPC1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4ACR, 4AD7, 4BWE, 4YWT
Identifiers
Aliases	GPC1, glypican, Glypican 1
External IDs	OMIM: 600395; MGI: 1194891; HomoloGene: 20477; GeneCards: GPC1; OMA:GPC1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	240,468,076 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	92,788,501 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; apex of heart; ; right hemisphere of cerebellum; ; skin of abdomen; ; stromal cell of endometrium; ; right frontal lobe; ; tibial nerve; ; skin of leg; ; left ventricle; ; periodontal fiber;
	Top expressed in
	calvaria; ; renal corpuscle; ; ankle; ; ventricular zone; ; muscle of thigh; ; myocardium of ventricle; ; temporal muscle; ; interventricular septum; ; sternum; ; triceps brachii muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	fibroblast growth factor binding; heparan sulfate proteoglycan binding; copper ion binding; laminin binding;
Cellular component	endosome; membrane; integral component of plasma membrane; lysosomal lumen; Golgi lumen; membrane raft; anchored component of membrane; extracellular exosome; extracellular space; nucleoplasm; cytosol; plasma membrane; extracellular matrix; extracellular region; intrinsic component of plasma membrane; synapse; anchored component of plasma membrane; collagen-containing extracellular matrix; cell surface;
Biological process	glycosaminoglycan metabolic process; myelin assembly; heparan sulfate proteoglycan catabolic process; retinoid metabolic process; axon guidance; negative regulation of fibroblast growth factor receptor signaling pathway; positive regulation of skeletal muscle cell differentiation; glycosaminoglycan catabolic process; glycosaminoglycan biosynthetic process; Schwann cell differentiation; leukocyte migration; regulation of signal transduction; cell migration; regulation of protein localization to membrane;
	Sources:Amigo / QuickGO
Orthologs
	2817
	14733
	ENSG00000063660
	ENSMUSG00000034220
	P35052
	Q9QZF2
	NM_002081
	NM_016696
	NP_002072
	NP_057905
	Wikidata
View/Edit Human	View/Edit Mouse

Glypican-1 (GPC1) is a protein that in humans is encoded by the GPC1 gene. GPC1 is encoded by human GPC1 gene located at 2q37.3. GPC1 contains 558 amino acids with three predicted heparan sulfate chains.