GPM6B

GPM6B
Identifiers
Aliases	GPM6B, M6B, glycoprotein M6B
External IDs	OMIM: 300051; MGI: 107672; HomoloGene: 128189; GeneCards: GPM6B; OMA:GPM6B - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	13,938,638 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	165,171,984 bp
RNA expression pattern
	Top expressed in
	dorsal motor nucleus of vagus nerve; ; external globus pallidus; ; inferior ganglion of vagus nerve; ; inferior olivary nucleus; ; subthalamic nucleus; ; Region I of hippocampus proper; ; pars reticulata; ; optic nerve; ; postcentral gyrus; ; pars compacta;
	Top expressed in
	lobe of cerebellum; ; dorsal striatum; ; olfactory tubercle; ; cerebellar vermis; ; optic nerve; ; globus pallidus; ; nucleus accumbens; ; deep cerebellar nuclei; ; prefrontal cortex; ; lateral septal nucleus;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	molecular function;
Cellular component	integral component of membrane; membrane raft; plasma membrane; membrane;
Biological process	regulation of focal adhesion assembly; protein transport; multicellular organism development; negative regulation of serotonin uptake; cell differentiation; negative regulation of protein localization to cell surface; regulation of actin cytoskeleton organization; extracellular matrix assembly; ossification; nervous system development; positive regulation of bone mineralization; neuron projection development;
	Sources:Amigo / QuickGO
Orthologs
	2824
	14758
	ENSG00000046653
	ENSMUSG00000031342
	Q13491
	P35803
	NM_001001994; NM_001001995; NM_001001996; NM_005278; NM_001318729
NM_001177955; NM_001177956; NM_001177957; NM_001177958; NM_001177959;
	NM_001177960; NM_001177961; NM_001177962; NM_023122
	NP_001001994; NP_001001995; NP_001001996; NP_001305658; NP_005269
NP_001171426; NP_001171427; NP_001171428; NP_001171429; NP_001171430;
	NP_001171431; NP_001171432; NP_001171433; NP_075611
	Wikidata
View/Edit Human	View/Edit Mouse

Neuronal membrane glycoprotein M6-b is a protein that in humans is encoded by the GPM6B gene.

In melanocytic cells, GPM6B gene expression may be regulated by MITF.