GPR17

GPR17
Identifiers
Aliases	GPR17, G protein-coupled receptor 17
External IDs	OMIM: 603071; MGI: 3584514; HomoloGene: 83191; GeneCards: GPR17; OMA:GPR17 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	127,652,639 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	32,082,689 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; sural nerve; ; gastric mucosa; ; muscle layer of sigmoid colon; ; Amygdala; ; right auricle of heart; ; body of uterus; ; left coronary artery; ; left ventricle; ; Descending thoracic aorta;
	Top expressed in
	lumbar subsegment of spinal cord; ; dentate gyrus of hippocampal formation granule cell; ; Rostral migratory stream; ; nucleus of stria terminalis; ; visual cortex; ; central gray substance of midbrain; ; anterior horn of spinal cord; ; temporal lobe; ; primary visual cortex; ; hippocampus proper;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; chemokine receptor activity; signal transducer activity; receptor serine/threonine kinase binding;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	G protein-coupled receptor signaling pathway; signal transduction; negative regulation of inflammatory response to antigenic stimulus; chemokine-mediated signaling pathway; immune system process; positive regulation of Rho protein signal transduction; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway; oligodendrocyte differentiation;
	Sources:Amigo / QuickGO
Orthologs
	2840
	574402
	ENSG00000144230
	ENSMUSG00000052229
	Q13304
	Q6NS65
	NM_005291; NM_001161415; NM_001161416; NM_001161417
	NM_001025381
	NP_001154887; NP_001154888; NP_001154889; NP_005282
	NP_001020552
	Wikidata
View/Edit Human	View/Edit Mouse

Uracil nucleotide/cysteinyl leukotriene receptor is a G protein-coupled receptor that in humans is encoded by the GPR17 gene located on chromosome 2 at position q21. The actual activating ligands for and some functions of this receptor are disputed.