GPR26

GPR26
Identifiers
Aliases	GPR26, G protein-coupled receptor 26
External IDs	OMIM: 604847; MGI: 2441758; HomoloGene: 17764; GeneCards: GPR26; OMA:GPR26 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	123,697,399 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	131,596,134 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; Brodmann area 23; ; pars compacta; ; pars reticulata; ; tendon of biceps brachii; ; middle temporal gyrus; ; Brodmann area 46; ; buccal mucosa cell; ; myocardium; ; myocardium of left ventricle;
	Top expressed in
	superior frontal gyrus; ; primary visual cortex; ; lumbar subsegment of spinal cord; ; dentate gyrus of hippocampal formation granule cell; ; islands of Calleja; ; amygdalohippocampal area; ; medial septal nucleus; ; dorsal cochlear nucleus; ; cortical amygdaloid nucleus; ; paraventricular nucleus of thalamus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	signal transducer activity; G protein-coupled receptor activity;
Cellular component	plasma membrane; membrane; integral component of membrane; intracellular anatomical structure;
Biological process	adenylate cyclase-activating G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	2849
	233919
	ENSG00000154478
	ENSMUSG00000040125
	Q8NDV2
	Q8BZA7
	NM_153442
	NM_173410
	NP_703143
	NP_775586
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 26 is a protein that in humans is encoded by the GPR26 gene. GPR26 expression is found to peak perinatally, when the visual system is first challenged, and contains a 53 kb LD-block enriched for association with introgressed Neanderthal-derived SNPs. Additionally, it is known to form oligomeric structures with the 5-HT1a receptor.