GPR35

GPR35
Identifiers
Aliases	GPR35, G protein-coupled receptor 35
External IDs	OMIM: 602646; MGI: 1929509; HomoloGene: 3874; GeneCards: GPR35; OMA:GPR35 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	240,633,159 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	92,914,113 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; mucosa of ileum; ; duodenum; ; jejunal mucosa; ; granulocyte; ; right uterine tube; ; monocyte; ; rectum; ; body of stomach; ; mucosa of sigmoid colon;
	Top expressed in
	zygote; ; lumbar spinal ganglion; ; primary oocyte; ; secondary oocyte; ; neural layer of retina; ; urethra; ; granulocyte; ; esophagus; ; yolk sac; ; colon;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; C-X-C chemokine receptor activity;
Cellular component	integral component of membrane; integral component of plasma membrane; membrane; plasma membrane;
Biological process	G protein-coupled receptor signaling pathway; signal transduction; cytoskeleton organization; positive regulation of cytosolic calcium ion concentration; positive regulation of Rho protein signal transduction; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway; chemokine-mediated signaling pathway; negative regulation of voltage-gated calcium channel activity; negative regulation of neuronal action potential;
	Sources:Amigo / QuickGO
Orthologs
	2859
	64095
	ENSG00000178623
	ENSMUSG00000026271
	Q9HC97
	Q9ES90
	NM_005301; NM_001195381; NM_001195382; NM_001394730
	NM_001104529; NM_001271766; NM_022320
	NP_001182310; NP_001182311; NP_005292
	NP_001097999; NP_001258695; NP_071715
	Wikidata
View/Edit Human	View/Edit Mouse

G protein-coupled receptor 35 also known as GPR35 is a G protein-coupled receptor which in humans is encoded by the GPR35 gene. Heightened expression of GPR35 is found in immune and gastrointestinal tissues, including the crypts of Lieberkühn.