GPR45

GPR45
Identifiers
Aliases	GPR45, PSP24, PSP24(ALPHA), PSP24A, G protein-coupled receptor 45
External IDs	OMIM: 604838; MGI: 2135882; HomoloGene: 5228; GeneCards: GPR45; OMA:GPR45 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	105,243,467 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	43,074,616 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; right frontal lobe; ; Brodmann area 9; ; cingulate gyrus; ; anterior cingulate cortex; ; Hypothalamus; ; nucleus accumbens; ; Amygdala; ; embryo; ; caudate nucleus;
	Top expressed in
	lumbar subsegment of spinal cord; ; ventricular zone; ; ganglionic eminence; ; arcuate nucleus; ; dentate gyrus of hippocampal formation granule cell; ; paraventricular nucleus of hypothalamus; ; primary visual cortex; ; dorsomedial hypothalamic nucleus; ; superior frontal gyrus; ; ventral tegmental area;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	signal transduction; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	11250
	93690
	ENSG00000135973
	ENSMUSG00000041907
	Q9Y5Y3
	Q9EQQ4
	NM_007227
	NM_053107
	NP_009158
	NP_444337
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 45 is a protein that in humans is encoded by the GPR45 gene.

This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system.