GPR52

GPR52
Identifiers
Aliases	GPR52, G protein-coupled receptor 52
External IDs	OMIM: 604106; MGI: 3643278; HomoloGene: 74561; GeneCards: GPR52; OMA:GPR52 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	174,449,545 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	160,405,544 bp
RNA expression pattern
	Top expressed in
	testicle; ; bone marrow cells; ; nucleus accumbens; ; prefrontal cortex; ; putamen; ; caudate nucleus; ; epithelium of colon; ; Achilles tendon; ; gonad; ; Brodmann area 9;
	Top expressed in
	striatum of neuraxis; ; superior frontal gyrus; ; embryo; ; primary visual cortex; ; Hypothalamus; ; dentate gyrus of hippocampal formation granule cell; ; hippocampus proper; ; duodenum; ; granulocyte; ; ileum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	dopamine neurotransmitter receptor activity, coupled via Gs; signal transducer activity; G protein-coupled receptor activity; G protein-coupled photoreceptor activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	G protein-coupled receptor signaling pathway; signal transduction; dopamine receptor signaling pathway; locomotory behavior; phototransduction; detection of visible light; cellular response to light stimulus;
	Sources:Amigo / QuickGO
Orthologs
	9293
	620246
	ENSG00000203737
	ENSMUSG00000118401
	Q9Y2T5
	P0C5J4
	NM_005684
	NM_001146330; NM_001368668
	NP_005675
	NP_001139802; NP_001355597
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 52 is a protein that in humans is encoded by the GPR52 gene.

Members of the G protein-coupled receptor (GPR) family play important roles in signal transduction from the external environment to the inside of the cell.[supplied by OMIM]

Cannabidiol, CBD, and O-1918 are Inverse agonist at GPR52.