GPR55

GPR55
Identifiers
Aliases	GPR55, LPIR1, G protein-coupled receptor 55
External IDs	OMIM: 604107; MGI: 2685064; HomoloGene: 36184; GeneCards: GPR55; OMA:GPR55 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	230,961,066 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	85,961,007 bp
RNA expression pattern
	Top expressed in
	monocyte; ; granulocyte; ; nucleus accumbens; ; lymph node; ; spleen; ; putamen; ; caudate nucleus; ; right testis; ; appendix; ; blood;
	Top expressed in
	jejunum; ; duodenum; ; ileum; ; colon; ; spermatocyte; ; testicle; ; adrenal gland; ; yolk sac; ; primary oocyte; ; spleen;
	More reference expression data
	n/a
Gene ontology
Molecular function	cannabinoid receptor activity; G protein-coupled receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	positive regulation of Rho protein signal transduction; G protein-coupled receptor signaling pathway; activation of phospholipase C activity; bone resorption; negative regulation of osteoclast differentiation; signal transduction; positive regulation of ERK1 and ERK2 cascade; cannabinoid signaling pathway; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	9290
	227326
	ENSG00000135898
	ENSMUSG00000049608
	Q9Y2T6
	Q3UJF0
	NM_005683
	NM_001033290
	NP_005674
	NP_001028462
	Wikidata
View/Edit Human	View/Edit Mouse

G protein-coupled receptor 55 also known as GPR55 is a G protein-coupled receptor that in humans is encoded by the GPR55 gene.

GPR55, along with GPR119 and GPR18, have been implicated as novel cannabinoid receptors.