Glutathione peroxidase 8

GPX8
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3CYN, 3KIJ
Identifiers
Aliases	GPX8, EPLA847, GPx-8, GSHPx-8, UNQ847, glutathione peroxidase 8 (putative)
External IDs	OMIM: 617172; MGI: 1916840; HomoloGene: 88454; GeneCards: GPX8; OMA:GPX8 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	55,167,297 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	113,182,944 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; tibia; ; germinal epithelium; ; placenta; ; smooth muscle tissue; ; Achilles tendon; ; parietal pleura; ; gonad; ; synovial membrane; ; corpus epididymis;
	Top expressed in
	calvaria; ; umbilical cord; ; efferent ductule; ; Epithelium of choroid plexus; ; vestibular sensory epithelium; ; decidua; ; interventricular septum; ; uterus; ; intercostal muscle; ; cervix;
	More reference expression data
	n/a
Gene ontology
Molecular function	oxidoreductase activity; glutathione peroxidase activity; peroxidase activity;
Cellular component	integral component of membrane; endoplasmic reticulum lumen; membrane;
Biological process	response to oxidative stress; cellular oxidant detoxification; cellular response to oxidative stress;
	Sources:Amigo / QuickGO
Orthologs
	493869
	69590
	ENSG00000164294
	ENSMUSG00000021760
	Q8TED1
	Q9D7B7
	NM_001008397; NM_001306197; NM_001306198; NM_001306201
	NM_027127
	NP_001008398; NP_001293126; NP_001293127; NP_001293130
	NP_081403
	Wikidata
View/Edit Human	View/Edit Mouse

Glutathione peroxidase 8 (GPx-8) is an enzyme that in humans is encoded by the GPX8 gene. GPx-8 is a member of the glutathione peroxidase family.