GRAP2

GRAP2
Identifiers
Aliases	GRAP2, GADS, GRAP-2, GRB2L, GRBLG, GRID, GRPL, GrbX, Grf40, Mona, P38, GRB2-related adaptor protein 2, GRB2 related adaptor protein 2
External IDs	OMIM: 604518; MGI: 1333842; HomoloGene: 21007; GeneCards: GRAP2; OMA:GRAP2 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	39,973,721 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	80,537,055 bp
RNA expression pattern
	Top expressed in
	monocyte; ; granulocyte; ; blood; ; thymus; ; lymph node; ; testicle; ; spleen; ; epithelium of colon; ; appendix; ; bone marrow cells;
	Top expressed in
	thymus; ; blood; ; spleen; ; yolk sac; ; embryo; ; mesenteric lymph nodes; ; granulocyte; ; genital tubercle; ; tail of embryo; ; seminiferous tubule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; non-membrane spanning protein tyrosine kinase activity; signaling receptor binding;
Cellular component	cytoplasm; cytosol; endosome; nucleus; extrinsic component of cytoplasmic side of plasma membrane;
Biological process	Fc-epsilon receptor signaling pathway; cell-cell signaling; T cell costimulation; Ras protein signal transduction; T cell receptor signaling pathway; positive regulation of signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; cell migration; cell differentiation; peptidyl-tyrosine autophosphorylation; regulation of cell population proliferation; innate immune response;
	Sources:Amigo / QuickGO
Orthologs
	9402
	17444
	ENSG00000100351
	ENSMUSG00000042351
	O75791
	O89100
	NM_001291824; NM_001291825; NM_001291826; NM_001291828; NM_004810
	NM_001289442; NM_010815
	NP_001278753; NP_001278754; NP_001278755; NP_001278757; NP_004801
	NP_001276371; NP_034945
	Wikidata
View/Edit Human	View/Edit Mouse

GRB2-related adapter protein 2 also known as GRB2-related adaptor downstream of Shc (GADS) is a 37 kDa protein that in humans is encoded by the GRAP2 gene.