GRB7

GRB7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3PQZ, 1MW4, 1WGR, 2L4K, 2QMS, 4WWQ, 4X6S, 5EEL, 5EEQ, 5D0J
Identifiers
Aliases	GRB7, entrez:2886, growth factor receptor bound protein 7
External IDs	OMIM: 601522; MGI: 102683; HomoloGene: 3881; GeneCards: GRB7; OMA:GRB7 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	39,747,291 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	98,346,199 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; right uterine tube; ; body of pancreas; ; skin of abdomen; ; skin of leg; ; minor salivary glands; ; olfactory zone of nasal mucosa; ; right lobe of liver; ; mucosa of transverse colon;
	Top expressed in
	Ileal epithelium; ; right kidney; ; genital tubercle; ; proximal tubule; ; corneal stroma; ; nasolacrimal duct; ; transitional epithelium of urinary bladder; ; yolk sac; ; left lobe of liver; ; tail of embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; phosphatidylinositol binding; identical protein binding; RNA binding; protein kinase binding; lipid binding;
Cellular component	cytoplasm; cytosol; cell projection; membrane; focal adhesion; plasma membrane; cell junction; cytoplasmic stress granule;
Biological process	negative regulation of translation; epidermal growth factor receptor signaling pathway; positive regulation of cell migration; leukocyte migration; signal transduction; stress granule assembly; ERBB2 signaling pathway; positive regulation of signal transduction; axon guidance; insulin receptor signaling pathway; negative regulation of insulin receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2886
	14786
	ENSG00000141738
	ENSMUSG00000019312
	Q14451
	Q03160
	NM_001030002; NM_001242442; NM_001242443; NM_005310; NM_001330207
	NM_010346
	NP_001025173; NP_001229371; NP_001229372; NP_001317136; NP_005301
	NP_034476
	Wikidata
View/Edit Human	View/Edit Mouse

Growth factor receptor-bound protein 7, also known as GRB7, is a protein that in humans is encoded by the GRB7 gene.