GRIN2C

GRIN2C
Identifiers
Aliases	GRIN2C, GluN2C, NMDAR2C, NR2C, glutamate ionotropic receptor NMDA type subunit 2C
External IDs	OMIM: 138254; MGI: 95822; HomoloGene: 647; GeneCards: GRIN2C; OMA:GRIN2C - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	74,861,504 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	115,158,069 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; paraflocculus of cerebellum; ; cerebellar vermis; ; parotid gland; ; right auricle of heart; ; putamen; ; right lobe of thyroid gland; ; Amygdala; ; caudate nucleus; ; right frontal lobe;
	Top expressed in
	lobe of cerebellum; ; cerebellar vermis; ; entorhinal cortex; ; perirhinal cortex; ; CA3 field; ; medial dorsal nucleus; ; visual cortex; ; granular layer; ; choroid plexus of fourth ventricle; ; lateral geniculate nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ion channel activity; protein binding; ionotropic glutamate receptor activity; cation channel activity; extracellularly glutamate-gated ion channel activity; NMDA glutamate receptor activity; glutamate-gated calcium ion channel activity; signaling receptor activity; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential;
Cellular component	integral component of membrane; postsynaptic membrane; membrane; postsynaptic density; plasma membrane; synapse; cell junction; intracellular anatomical structure; integral component of plasma membrane; NMDA selective glutamate receptor complex; postsynaptic density membrane; glutamatergic synapse;
Biological process	protein localization; glutamate receptor signaling pathway; neuromuscular process controlling balance; negative regulation of protein catabolic process; regulation of membrane potential; directional locomotion; ion transport; MAPK cascade; ionotropic glutamate receptor signaling pathway; response to wounding; excitatory postsynaptic potential; calcium-mediated signaling; calcium ion transmembrane import into cytosol; regulation of molecular function; transport; brain development; regulation of synaptic plasticity; long-term potentiation; excitatory chemical synaptic transmission; protein localization to postsynaptic membrane;
	Sources:Amigo / QuickGO
Orthologs
	2905
	14813
	ENSG00000161509
	ENSMUSG00000020734
	Q14957
	Q01098
	NM_000835; NM_001278553
	NM_010350
	NP_000826; NP_001265482
	NP_034480
	Wikidata
View/Edit Human	View/Edit Mouse

Glutamate [NMDA] receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene.