GRIN2D

GRIN2D
Identifiers
Aliases	GRIN2D, EB11, GluN2D, NMDAR2D, NR2D, glutamate ionotropic receptor NMDA type subunit 2D, EIEE46, DEE46
External IDs	OMIM: 602717; MGI: 95823; HomoloGene: 648; GeneCards: GRIN2D; OMA:GRIN2D - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	48,444,931 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	45,878,378 bp
RNA expression pattern
	Top expressed in
	cingulate gyrus; ; anterior cingulate cortex; ; prefrontal cortex; ; ganglionic eminence; ; Hypothalamus; ; ventricular zone; ; right frontal lobe; ; lateral nuclear group of thalamus; ; Amygdala; ; dorsolateral prefrontal cortex;
	Top expressed in
	molecular layer of cerebellar cortex; ; lumbar subsegment of spinal cord; ; molar; ; primary visual cortex; ; seminiferous tubule; ; dorsomedial hypothalamic nucleus; ; superior frontal gyrus; ; spermatocyte; ; dentate gyrus of hippocampal formation granule cell; ; neural layer of retina;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ion channel activity; protein binding; extracellularly glutamate-gated ion channel activity; ionotropic glutamate receptor activity; NMDA glutamate receptor activity; glutamate-gated calcium ion channel activity; signaling receptor activity;
Cellular component	integral component of membrane; postsynaptic membrane; membrane; plasma membrane; synapse; cell junction; intracellular anatomical structure; integral component of plasma membrane; NMDA selective glutamate receptor complex; postsynaptic density membrane;
Biological process	startle response; regulation of sensory perception of pain; adult locomotory behavior; ion transport; MAPK cascade; ionotropic glutamate receptor signaling pathway; excitatory postsynaptic potential; calcium-mediated signaling; calcium ion transmembrane import into cytosol; regulation of molecular function; brain development; regulation of synaptic plasticity; long-term potentiation; excitatory chemical synaptic transmission;
	Sources:Amigo / QuickGO
Orthologs
	2906
	14814
	ENSG00000105464
	ENSMUSG00000002771
	O15399
	Q03391
	NM_000836
	NM_008172
	NP_000827
	NP_032198
	Wikidata
View/Edit Human	View/Edit Mouse

Glutamate [NMDA] receptor subunit epsilon-4 is a protein that in humans is encoded by the GRIN2D gene.