Metabotropic glutamate receptor 7

GRM7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3MQ4, 5C5C
Identifiers
Aliases	GRM7, GLUR7, GPRC1G, MGLU7, MGLUR7, PPP1R87, glutamate metabotropic receptor 7, NEDSHBA
External IDs	OMIM: 604101; MGI: 1351344; HomoloGene: 20233; GeneCards: GRM7; OMA:GRM7 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	7,741,533 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	111,544,191 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; middle temporal gyrus; ; Region I of hippocampus proper; ; Brodmann area 23; ; entorhinal cortex; ; olfactory zone of nasal mucosa; ; sperm; ; orbitofrontal cortex; ; dorsolateral prefrontal cortex; ; Brodmann area 9;
	Top expressed in
	medial dorsal nucleus; ; superior colliculus; ; mammillary body; ; olfactory tubercle; ; medial geniculate nucleus; ; piriform cortex; ; subiculum; ; ventromedial nucleus; ; substantia nigra; ; nucleus accumbens;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	glutamate receptor activity; calcium ion binding; PDZ domain binding; serine binding; G protein-coupled receptor activity; group III metabotropic glutamate receptor activity; adenylate cyclase inhibitor activity; signal transducer activity; glutamate binding; calcium channel regulator activity;
Cellular component	integral component of membrane; postsynaptic membrane; membrane; receptor complex; plasma membrane; integral component of plasma membrane; dendritic shaft; presynaptic active zone; axon; dendrite; cell cortex; asymmetric synapse; presynaptic membrane;
Biological process	negative regulation of glutamate secretion; response to stimulus; hearing; behavioral fear response; adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway; signal transduction; regulation of cyclase activity; regulation of synaptic transmission, glutamatergic; chemical synaptic transmission; G protein-coupled receptor signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; G protein-coupled glutamate receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2917
	108073
	ENSG00000196277
	ENSMUSG00000056755
	Q14831
	Q68ED2
	NM_000844; NM_181874; NM_181875
	NM_177328; NM_001346640; NM_177970
	NP_000835; NP_870989
	NP_001333569; NP_796302
	Wikidata
View/Edit Human	View/Edit Mouse

Metabotropic glutamate receptor 7 is a protein that in humans is encoded by the GRM7 gene.