Metabotropic glutamate receptor 8

GRM8
Identifiers
Aliases	GRM8, GLUR8, GPRC1H, MGLUR8, mGlu8, glutamate metabotropic receptor 8
External IDs	OMIM: 601116; MGI: 1351345; HomoloGene: 654; GeneCards: GRM8; OMA:GRM8 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	127,253,093 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	28,135,177 bp
RNA expression pattern
	Top expressed in
	gonad; ; testicle; ; left testis; ; right testis; ; oocyte; ; Epithelium of choroid plexus; ; prefrontal cortex; ; Brodmann area 9; ; corpus callosum; ; cingulate gyrus;
	Top expressed in
	ganglion cell layer; ; secondary oocyte; ; zygote; ; inner nuclear layer; ; superior frontal gyrus; ; embryo; ; primary visual cortex; ; embryo; ; outer nuclear layer; ; dentate gyrus of hippocampal formation granule cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	glutamate receptor activity; G protein-coupled receptor activity; signal transducer activity;
Cellular component	integral component of membrane; integral component of plasma membrane; presynaptic membrane; membrane; plasma membrane;
Biological process	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway; signal transduction; visual perception; response to stimulus; regulation of synaptic transmission, glutamatergic; G protein-coupled receptor signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; G protein-coupled glutamate receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2918
	14823
	ENSG00000179603
	ENSMUSG00000024211
	O00222
	P47743
NM_000845; NM_001127323; NM_001371083; NM_001371084; NM_001371085;
	NM_001371086; NM_001371087; NM_001371088
	NM_008174; NM_001311072; NM_001361125
NP_000836; NP_001120795; NP_001358012; NP_001358013; NP_001358014;
	NP_001358015; NP_001358016; NP_001358017
	NP_001298001; NP_032200; NP_001348054
	Wikidata
View/Edit Human	View/Edit Mouse

Metabotropic glutamate receptor 8 is a protein that in humans is encoded by the GRM8 gene.