GSTT2

GSTT2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4MPF
Identifiers
Aliases	GSTT2, GSTT2B, glutathione S-transferase theta 2 (gene/pseudogene)
External IDs	OMIM: 600437; MGI: 106188; HomoloGene: 37358; GeneCards: GSTT2; OMA:GSTT2 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	23,983,915 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	75,673,258 bp
RNA expression pattern
	Top expressed in
	testicle; ; stromal cell of endometrium; ; superior frontal gyrus; ; prefrontal cortex; ; fundus; ; right adrenal cortex; ; apex of heart; ; primary visual cortex; ; left adrenal gland; ; ascending aorta;
	Top expressed in
	right kidney; ; human kidney; ; proximal tubule; ; duodenum; ; left lobe of liver; ; spermatocyte; ; yolk sac; ; cervix; ; embryo; ; transitional epithelium of urinary bladder;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; glutathione transferase activity;
Cellular component	extracellular exosome; cytoplasm;
Biological process	glutathione metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	2953
	14872
	ENSG00000099984; ENSG00000277897
	ENSMUSG00000033318
	P0CG29
	Q61133
	NM_000854; NM_001302670
	NM_010361
	NP_000845; NP_001289599
	NP_034491
	Wikidata
View/Edit Human	View/Edit Mouse

Glutathione S-transferase theta-2 is an enzyme that in humans is encoded by the GSTT2 gene.

Glutathione S-transferase (GSTs) theta 2 (GSTT2) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: Alpha, Mu, Pi, Theta, and Zeta. The theta class members GSTT1 and GSTT2 share 55% amino acid sequence identity and both are thought to have an important role in human carcinogenesis. The theta genes have a similar structure, being composed of five exons with identical exon/intron boundaries.