GUK1

GUK1
Identifiers
Aliases	GUK1, GMK, guanylate kinase 1
External IDs	OMIM: 139270; MGI: 95871; HomoloGene: 665; GeneCards: GUK1; OMA:GUK1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	228,148,984 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	59,083,038 bp
RNA expression pattern
	Top expressed in
	right frontal lobe; ; prefrontal cortex; ; Amygdala; ; C1 segment; ; skin of leg; ; skin of abdomen; ; nucleus accumbens; ; right lung; ; caudate nucleus; ; ascending aorta;
	Top expressed in
	neural layer of retina; ; facial motor nucleus; ; dentate gyrus of hippocampal formation granule cell; ; right kidney; ; islet of Langerhans; ; epithelium of lens; ; esophagus; ; superior frontal gyrus; ; anterior horn of spinal cord; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	ATP binding; kinase activity; nucleotide binding; transferase activity; guanylate kinase activity;
Cellular component	cytosol;
Biological process	dGMP metabolic process; purine nucleotide metabolic process; nucleobase-containing small molecule interconversion; glycoprotein transport; GMP metabolic process; ATP metabolic process; nucleotide phosphorylation; GDP biosynthetic process; dGDP biosynthetic process; dATP metabolic process; phosphorylation; GDP-mannose metabolic process; GDP metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	2987
	14923
	ENSG00000143774
	ENSMUSG00000020444
	Q16774; Q6IBG8
	Q64520
	NM_000858; NM_001159390; NM_001159391; NM_001242839; NM_001242840
	NM_001159410; NM_008193
NP_000849; NP_001152862; NP_001152863; NP_001229768; NP_001229769;
	NP_000849.1; NP_001152862.1; NP_001152863.1; NP_001229768.1
NP_001152882; NP_032219; NP_001390762; NP_001390763; NP_001390764;
	NP_001390765; NP_001390766
	Wikidata
View/Edit Human	View/Edit Mouse

Guanylate kinase is an enzyme that in humans is encoded by the GUK1 gene.