Glutarimide

Glutarimide
Names
Preferred IUPAC name
Piperidine-2,6-dione
Other names
NSC 58190,EINECS 214-340-4,BRN 0110052
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.013.038
UNII
  • InChI=1S/C5H7NO2/c7-4-2-1-3-5(8)6-4/h1-3H2,(H,6,7,8)
    Key: KNCYXPMJDCCGSJ-UHFFFAOYSA-N
  • C1CC(=O)NC(=O)C1
Properties
C5H7NO2
Molar mass 113.11 g/mol
Appearance White crystalline powder
Melting point 155-157 °C
Soluble in water, ethanol, acetone
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Glutarimide, also known as piperidine-2,6-dione, is an organic compound with the chemical formula C5H7NO2. It is a white crystalline powder formed by the dehydration of the amide of glutaric acid. Glutarimide serves as a core structural component in several pharmacologically active compounds, including thalidomide, lenalidomide, cycloheximide, and glutethimide, which exhibit immunomodulatory, anticancer, or antibiotic properties. As a standalone compound, glutarimide is used in chemical synthesis and research, with no direct therapeutic applications.

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