Glycine

Glycine
Skeletal formula of neutral glycine	Skeletal formula of zwitterionic glycine
Ball-and-stick model of the gas-phase structure	Ball-and-stick model of the zwitterionic solid-state structure
Space-filling model of the gas-phase structure	Space-filling model of the zwitterionic solid-state structure
Names
	IUPAC name Glycine
	Systematic IUPAC name Aminoacetic acid
	Other names 2-Aminoethanoic acid; Glycocol; Glycic acid; Dicarbamic acid;
Identifiers
CAS Number	56-40-6 ; 6000-43-7 (HCl salt) ;
3D model (JSmol)	Interactive image; Zwitterion: Interactive image; Interactive image;
Abbreviations	Gly, G
ChEBI	CHEBI:15428 ;
ChEMBL	ChEMBL773 ;
ChemSpider	730 ; 20944;
DrugBank	DB00145 ;
ECHA InfoCard	100.000.248
EC Number	200-272-2; 227-841-8;
E number	E640 (flavour enhancer)
IUPHAR/BPS	727;
KEGG	D00011 ;
PubChem CID	750; 22316;
UNII	TE7660XO1C ; 225ZLC74HX ;
CompTox Dashboard (EPA)	DTXSID9020667 ;
	InChI InChI=1S/C2H5NH2/c3-1-2(4)5/h1,3H2,(H,4,5) Key: DHMQDGOQFOQNFH-UHFFFAOYSA-N ; InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5) Key: DHMQDGOQFOQNFH-UHFFFAOYAW;
	SMILES C(C(=O)O)N; Zwitterion: C(C(=O)[O-])[NH3+]; C(C(=O)O)N.Cl;
Properties
Chemical formula	C2H5NO2
Molar mass	75.067 g·mol−1
Appearance	White solid
Density	1.1607 g/cm3
Melting point	233 °C (451 °F; 506 K) (decomposition)
Solubility in water	249.9 g/L (25 °C)
Solubility	soluble in pyridine ; sparingly soluble in ethanol ; insoluble in ether
Acidity (pKa)	2.34 (carboxyl), 9.6 (amino)
Magnetic susceptibility (χ)	−40.3·10−6 cm3/mol
Pharmacology
ATC code	B05CX03 (WHO)
Hazards
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	2600 mg/kg (mouse, oral)
Supplementary data page
	Glycine (data page)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Glycine (symbol Gly or G; /ˈɡlaɪsiːn/ ^ⓘ) is an amino acid that has a single hydrogen atom as its side chain. It is the simplest stable amino acid. Glycine is one of the proteinogenic amino acids. It is encoded by all the codons starting with GG (GGU, GGC, GGA, GGG). Glycine disrupts the formation of alpha-helices in secondary protein structure. Its small side chain causes it to favor random coils instead. Glycine is also an inhibitory neurotransmitter – interference with its release within the spinal cord (such as during a Clostridium tetani infection) can cause spastic paralysis due to uninhibited muscle contraction.

It is the only achiral proteinogenic amino acid. It can fit into both hydrophilic and hydrophobic environments, due to its minimal side chain of only one hydrogen atom.