Glycochenodeoxycholic acid

Glycochenodeoxycholic acid
Names
	IUPAC name N-(3α,7α-Dihydroxy-5β-cholan-24-oyl)glycine
	Systematic IUPAC name {(4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11aR)-4,7-Dihydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanamido}acetic acid
Identifiers
CAS Number	640-79-9 ;
3D model (JSmol)	Interactive image;
ChemSpider	12027 ;
IUPHAR/BPS	4545;
PubChem CID	12544;
UNII	451ZNJ667Y ;
CompTox Dashboard (EPA)	DTXSID301020165 ;
	InChI InChI=1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26-/m1/s1 Key: GHCZAUBVMUEKKP-GYPHWSFCSA-N ;
	SMILES C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C;
Properties
Chemical formula	C26H43NO5
Molar mass	449.62 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Glycochenodeoxycholic acid is a bile salt formed in the liver from chenodeoxycholic acid and glycine, usually found as the sodium salt. It acts as a detergent to solubilize fats for absorption.

Positive associations were observed between prediagnostic plasma levels of seven different conjugated bile acid metabolites, including glycochenodeoxycholic acid, and colon cancer risk. These findings support experimental data suggesting that a high bile acid load promotes colon cancer.