Glyoxylate reductase

Glyoxylate Reductase
The crystal structure of glyoxylate reductase complexed with NADPH. Each color represents a monomer of the enzyme. This enzyme was isolated from a hyperthermophilic archaeon, Pyrococcus horikoshii OT3. Image created by PyMOL.
Identifiers
EC no.1.1.1.26
CAS no.9028-32-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Glyoxylate reductase (EC 1.1.1.26), first isolated from spinach leaves, is an enzyme that catalyzes the reduction of glyoxylate to glycolate, using the cofactor NADH or NADPH.

The systematic name of this enzyme class is glycolate:NAD+ oxidoreductase. Other names in common use include NADH-glyoxylate reductase, glyoxylic acid reductase, and NADH-dependent glyoxylate reductase.