Guanidine
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| Names | |||
|---|---|---|---|
| Preferred IUPAC name Guanidine | |||
| Other names Iminomethanediamine | |||
| Identifiers | |||
| 3D model (JSmol) | |||
| 506044 | |||
| ChEBI | |||
| ChEMBL | |||
| ChemSpider | |||
| DrugBank | |||
| ECHA InfoCard | 100.003.656 | ||
| EC Number | 
 | ||
| 100679 | |||
| MeSH | Guanidine | ||
| PubChem CID | |||
| UNII | |||
| CompTox Dashboard (EPA) | |||
| 
 | |||
| 
 | |||
| Properties | |||
| CH5N3 | |||
| Molar mass | 59.072 g·mol−1 | ||
| Melting point | 50 °C (122 °F; 323 K) | ||
| log P | −1.251 | ||
| Basicity (pKb) | 0.4 | ||
| Conjugate acid | Guanidinium | ||
| Thermochemistry | |||
| Std enthalpy of formation (ΔfH⦵298) | −57 – −55 kJ mol−1 | ||
| Std enthalpy of combustion (ΔcH⦵298) | −1.0511 – −1.0531 MJ mol−1 | ||
| Pharmacology | |||
| Pharmacokinetics: | |||
| 7–8 hours | |||
| Hazards | |||
| Lethal dose or concentration (LD, LC): | |||
| LD50 (median dose) | 475 mg/kg (oral, rat) | ||
| Related compounds | |||
| Related compounds | |||
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references | |||
Guanidine is the compound with the formula HNC(NH2)2. It is a colourless solid that dissolves in polar solvents. It is a strong base that is used in the production of plastics and explosives. It is found in urine predominantly in patients experiencing renal failure. A guanidine moiety also appears in larger organic molecules, including on the side chain of arginine.