H1FX

H1-10
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2LSO
Identifiers
Aliases	H1-10, H1X, H1.10, H1 histone family member X, H1FX, H1.10 linker histone
External IDs	OMIM: 602785; MGI: 2685307; HomoloGene: 4397; GeneCards: H1-10; OMA:H1-10 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	129,316,286 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	87,958,619 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; olfactory zone of nasal mucosa; ; thymus; ; ectocervix; ; right ovary; ; skin of abdomen; ; right uterine tube; ; left ovary; ; left uterine tube;
	Top expressed in
	ventricular zone; ; adrenal medulla; ; ganglionic eminence; ; white adipose tissue; ; striatum of neuraxis; ; lens; ; testicle; ; neural tube; ; primary visual cortex; ; superior frontal gyrus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; RNA binding; cadherin binding; double-stranded DNA binding; protein binding; nucleosomal DNA binding;
Cellular component	nucleosome; nucleolus; nucleus; chromosome;
Biological process	nucleosome assembly; regulation of transcription, DNA-templated; chromosome condensation; negative regulation of DNA recombination;
	Sources:Amigo / QuickGO
Orthologs
	8971
	243529
	ENSG00000184897
	ENSMUSG00000044927
	Q92522
	Q80ZM5
	NM_006026
	NM_198622
	NP_006017
	NP_941024
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H1x is a protein that in humans is encoded by the H1FX gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H1 family.