HIST1H2AA

H2AC1
Identifiers
Aliases	H2AC1, H2AA, H2AFR, bA317E16.2, TH2A, histone cluster 1, H2aa, histone cluster 1 H2A family member a, HIST1H2AA, H2A clustered histone 1, HISTH2AA
External IDs	OMIM: 613499; MGI: 2448297; HomoloGene: 108269; GeneCards: H2AC1; OMA:H2AC1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	25,726,562 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	21,937,997 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; left testis; ; right testis; ; liver; ; right lobe of liver; ; human kidney; ; body of pancreas; ; renal cortex; ; respiratory system;
	Top expressed in
	uterus; ; genital tubercle; ; spermatid; ; Mesencephalon; ; tail of embryo; ; embryo; ; embryo; ; bone marrow; ; yolk sac; ; thymus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein heterodimerization activity; DNA binding;
Cellular component	nucleosome; nucleus; chromosome; extracellular exosome;
Biological process	chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	221613
	319169
	ENSG00000164508
	ENSMUSG00000063021
	Q96QV6
	Q8CGP7
	NM_170745
	NM_178183
	NP_734466
	NP_835490
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H2A type 1-A is a protein that in humans is encoded by the HIST1H2AA gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element.