HIST1H2AH

H2AC12
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2F8N
Identifiers
Aliases	H2AC12, H2A/S, H2AFALii, H2AH, dJ86C11.1, histone cluster 1, H2ah, histone cluster 1 H2A family member h, HIST1H2AH, H2A clustered histone 12
External IDs	OMIM: 615013; MGI: 2448295; HomoloGene: 119667; GeneCards: H2AC12; OMA:H2AC12 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	27,147,562 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	22,219,738 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; Achilles tendon; ; epithelium of colon; ; corpus callosum; ; tonsil; ; sural nerve; ; granulocyte; ; ventricular zone; ; mucosa of transverse colon; ; right testis;
	Top expressed in
	uterus; ; yolk sac; ; spermatid; ; embryo; ; bone marrow; ; embryo; ; morula; ; spermatocyte; ; thymus; ; zygote;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein heterodimerization activity; DNA binding; molecular function;
Cellular component	nucleosome; extracellular exosome; nucleus; chromosome;
Biological process	chromatin organization; biological process;
	Sources:Amigo / QuickGO
Orthologs
	85235
	319168
	ENSG00000274997
	ENSMUSG00000069302
	Q96KK5
	Q8CGP6
	NM_080596
	NM_175659
	NP_542163
	NP_783590
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H2A type 1-H is a protein that in humans is encoded by the HIST1H2AH gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.