HIST1H2AK

H2AC15
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4QYL, 5KGF
Identifiers
Aliases	H2AC15, H2A/d, H2AFD, histone cluster 1, H2ak, histone cluster 1 H2A family member k, HIST1H2AK, H2A clustered histone 15, H2AC11, H2AC14, H2AC17, H2AC16, H2AC13, H2A.1
External IDs	OMIM: 602788; MGI: 2448287; HomoloGene: 134305; GeneCards: H2AC15; OMA:H2AC15 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	27,838,375 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	23,867,931 bp
RNA expression pattern
	Top expressed in
	testicle; ; trachea; ; vastus lateralis muscle; ; Thalamus; ; spinal ganglia; ; epithelium of bronchus; ; paraflocculus of cerebellum; ; middle frontal gyrus; ; frontal pole; ; bone marrow cells;
	Top expressed in
	granulocyte; ; bone marrow; ; uterus; ; embryo; ; yolk sac; ; secondary oocyte; ; primary oocyte; ; zygote; ; lens; ; quadriceps femoris muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	enzyme binding; DNA binding; protein binding; protein heterodimerization activity;
Cellular component	nucleosome; extracellular exosome; nucleus; chromosome;
Biological process	chromatin organization; biological process;
	Sources:Amigo / QuickGO
Orthologs
	8330
	319164
	ENSG00000275221
	ENSMUSG00000069270
	P0C0S8
C0HKE2; B2RVF0; C0HKE1; C0HKE3; C0HKE4;
	C0HKE5; C0HKE6; C0HKE7; C0HKE8; C0HKE9
	NM_003510
	NM_178189
	NP_066408; NP_003505
NP_835496; NP_835495; NP_835494; NP_835491; NP_835489;
	NP_783591; NP_835493; NP_835496; NP_835489; NP_835495; NP_835494; NP_835491; NP_835492; NP_783591; NP_001171015; NP_835489; NP_001171015; NP_835496; NP_835491; NP_835493; NP_835494; NP_835495; NP_835492; NP_783591; NP_835494; NP_835489; NP_835495; NP_835491; NP_835492; NP_783591; NP_001171015; NP_835493; NP_835496; NP_835495; NP_835489; NP_835494; NP_835491; NP_835492; NP_783591; NP_001171015; NP_835493; NP_835496; NP_835492; NP_835491; NP_835489; NP_835495; NP_835494; NP_783591; NP_001171015; NP_835493; NP_835496; NP_835491; NP_835489; NP_835495; NP_835494; NP_835492; NP_783591; NP_001171015; NP_835493; NP_835496; NP_783591; NP_835489; NP_835495; NP_835494; NP_835491; NP_835492; NP_001171015; NP_835493; NP_835496; NP_783591; NP_835489; NP_835495; NP_835494; NP_835491; NP_835492; NP_001171015; NP_835493; NP_835496
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H2A type 1 is a protein that in humans is encoded by the HIST1H2AK gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.