HIST1H2AL

H2AC16
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesH2AC16, H2A.i, H2A/i, H2AFI, dJ193B12.9, histone cluster 1, H2al, histone cluster 1 H2A family member l, H2A clustered histone 16, HIST1H2AL, H2AC11, H2AC15, H2AC17, H2AC13
External IDsOMIM: 602793; MGI: 2448290; HomoloGene: 136768; GeneCards: H2AC16; OMA:H2AC16 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

8332

319166

Ensembl

ENSG00000276903

ENSMUSG00000069272

UniProt

P0C0S8

RefSeq (mRNA)

NM_003511

NM_178187

RefSeq (protein)

NP_066408
NP_003505

Location (UCSC)Chr 6: 27.87 – 27.87 MbChr 13: 23.75 – 23.76 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Histone H2A type 1 is a protein that in humans is encoded by the HIST1H2AL gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.