HIST3H2A

H2AW
Identifiers
Aliases	H2AW, histone cluster 3 H2A, HIST3H2A, H2A.W histone
External IDs	OMIM: 615015; MGI: 2448458; HomoloGene: 137357; GeneCards: H2AW; OMA:H2AW - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	228,457,873 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	58,847,656 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; right hemisphere of cerebellum; ; testicle; ; ganglionic eminence; ; left adrenal cortex; ; apex of heart; ; right adrenal gland; ; right adrenal cortex; ; gonad; ; ventricular zone;
	Top expressed in
	spermatocyte; ; retinal pigment epithelium; ; neural layer of retina; ; medial ganglionic eminence; ; lens; ; epithelium of lens; ; external carotid artery; ; ciliary body; ; olfactory bulb; ; trigeminal ganglion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein heterodimerization activity; protein binding;
Cellular component	nucleosome; extracellular exosome; nucleus; chromosome;
Biological process	nucleosome disassembly; UV-damage excision repair; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	92815
	319162
	ENSG00000181218; ENSG00000284841
	ENSMUSG00000078851
	Q7L7L0
	Q8BFU2
	NM_033445
	NM_178218
	NP_254280
	NP_835736
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H2A type 3 is a protein that in humans is encoded by the HIST3H2A gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element.