HIST1H2BL

H2BC13
Identifiers
Aliases	H2BC13, H2B/c, H2BFC, dJ97D16.4, histone cluster 1, H2bl, histone cluster 1 H2B family member l, H2B clustered histone 13, HIST1H2BL
External IDs	OMIM: 602800; MGI: 2448388; HomoloGene: 136771; GeneCards: H2BC13; OMA:H2BC13 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	27,807,929 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	22,227,846 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; testicle; ; Achilles tendon; ; epithelium of colon; ; gonad; ; monocyte; ; tonsil; ; granulocyte; ; mucosa of transverse colon; ; ganglionic eminence;
	Top expressed in
	zygote; ; secondary oocyte; ; primary oocyte; ; uterus; ; bone marrow; ; spermatid; ; genital tubercle; ; embryo; ; embryo; ; spermatocyte;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein heterodimerization activity; DNA binding;
Cellular component	nucleosome; nucleus; chromosome; extracellular exosome; nucleoplasm; cytosol;
Biological process	nucleosome assembly; protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	8340
	319183
	ENSG00000185130
	ENSMUSG00000069300
	Q99880
	P10853
	NM_003519
	NM_178198
	NP_003510
NP_835505; NP_001091448; NP_001300809; NP_001104025; NP_001300807;
	NP_835502; NP_835506; NP_835508
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H2B type 1-L is a protein that in humans is encoded by the HIST1H2BL gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.