HIST1H2BM

H2BC14
Identifiers
Aliases	H2BC14, H2B/e, H2BFE, dJ160A22.3, histone cluster 1, H2bm, histone cluster 1 H2B family member m, HIST1H2BM, H2B clustered histone 14
External IDs	OMIM: 602802; MGI: 2448407; HomoloGene: 136772; GeneCards: H2BC14; OMA:H2BC14 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	27,815,489 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	21,938,673 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; ventricular zone; ; epithelium of colon; ; tonsil; ; thymus; ; ganglionic eminence; ; mucosa of transverse colon; ; blood; ; lymph node; ; corpus callosum;
	Top expressed in
	genital tubercle; ; uterus; ; spermatid; ; bone marrow; ; embryo; ; embryo; ; spermatocyte; ; primary oocyte; ; tail of embryo; ; thymus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein heterodimerization activity; DNA binding;
Cellular component	nucleosome; nucleus; chromosome; extracellular exosome; nucleoplasm; cytosol;
Biological process	nucleosome assembly; protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	8342
	319187
	ENSG00000273703
	ENSMUSG00000095217
	Q99879
	P10853
	NM_003521
	NM_178201
	NP_003512
NP_835505; NP_001091448; NP_001300809; NP_001104025; NP_001300807;
	NP_835502; NP_835506; NP_835508
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H2B type 1-M is a protein that in humans is encoded by the HIST1H2BM gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.