HIST1H2BN

H2BC15
Identifiers
Aliases	H2BC15, H2B/d, H2BFD, histone cluster 1, H2bn, histone cluster 1 H2B family member n, H2B clustered histone 15, HIST1H2BN
External IDs	OMIM: 602801; MGI: 2448404; HomoloGene: 135961; GeneCards: H2BC15; OMA:H2BC15 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	27,855,709 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	21,906,737 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; epithelium of colon; ; monocyte; ; Achilles tendon; ; stromal cell of endometrium; ; tonsil; ; ventricular zone; ; C1 segment; ; striated muscle tissue; ; skeletal muscle tissue;
	Top expressed in
	spermatid; ; genital tubercle; ; spermatocyte; ; tail of embryo; ; uterus; ; zygote; ; embryo; ; embryo; ; bone marrow; ; morula;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein heterodimerization activity;
Cellular component	chromosome; nucleosome; extracellular exosome; nucleus; nucleoplasm; cytosol;
Biological process	nucleosome assembly; protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	8341
	319186
	ENSG00000233822
	ENSMUSG00000114279
	Q99877
	P10854
	NM_003520
	NM_178200
	NP_003511
	NP_835507
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H2B type 1-N is a protein that in humans is encoded by the HIST1H2BN gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.