HIST3H2BB

H2BU1
Identifiers
Aliases	H2BU1, H2Bb, histone cluster 3, H2bb, histone cluster 3 H2B family member b, H2B.U histone 1, HIST3H2BB
External IDs	OMIM: 615046; MGI: 1922442; HomoloGene: 75941; GeneCards: H2BU1; OMA:H2BU1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	228,463,104 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	58,845,254 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; right uterine tube; ; Cerebellum; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; ganglionic eminence; ; ventricular zone; ; olfactory zone of nasal mucosa; ; gonad; ; prefrontal cortex;
	Top expressed in
	ganglionic eminence; ; spermatocyte; ; epiblast; ; dentate gyrus of hippocampal formation granule cell; ; ventricular zone; ; embryo; ; Mesencephalon; ; lens; ; neural tube; ; proximal tubule;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein heterodimerization activity; molecular function;
Cellular component	chromosome; nucleosome; nucleus; nucleoplasm; cytosol;
Biological process	nucleosome assembly;
	Sources:Amigo / QuickGO
Orthologs
	128312
	382522
	ENSG00000196890; ENSG00000285449
	ENSMUSG00000080712
	Q8N257
	n/a
	NM_175055
	NM_001393523
	NP_778225
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H2B type 3-B is a protein that in humans is encoded by the HIST3H2BB gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 base pairs (bp) of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene contain a palindromic termination element.