HIST1H2BG

H2BC8
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5KGF
Identifiers
Aliases	H2BC8, H2B.1A, H2B/a, H2BFA, dJ221C16.8, histone cluster 1, H2bg, histone cluster 1 H2B family member g, HIST1H2BG, H2B clustered histone 8, H2BC10, H2BC7, H2BC6, H2BC4
External IDs	OMIM: 602798; MGI: 2448383; HomoloGene: 136770; GeneCards: H2BC8; OMA:H2BC8 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	26,216,688 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	23,758,370 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; thymus; ; corpus epididymis; ; bone marrow cells; ; gonad; ; amniotic fluid; ; monocyte; ; testicle; ; caput epididymis; ; epithelium of colon;
	Top expressed in
	uterus; ; blastocyst; ; genital tubercle; ; tail of embryo; ; embryo; ; embryo; ; spermatocyte; ; yolk sac; ; zygote; ; thymus;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; protein binding; protein heterodimerization activity; identical protein binding;
Cellular component	chromosome; nucleosome; extracellular exosome; nucleus; nucleoplasm; extracellular space; cytosol;
Biological process	nucleosome assembly; innate immune response in mucosa; defense response to bacterium; protein ubiquitination; antimicrobial humoral immune response mediated by antimicrobial peptide;
	Sources:Amigo / QuickGO
Orthologs
	8339
	319180
	ENSG00000273802
	ENSMUSG00000069268
	P62807
	P10853
	NM_003518
	NM_178195
	NP_003517; NP_001368918
NP_835505; NP_001091448; NP_001300809; NP_001104025; NP_001300807;
	NP_835502; NP_835506; NP_835508
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H2B type 1-C/E/F/G/I is a protein that in humans is encoded by the HIST1H2BG gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.