HIST1H2BH

H2BC9
Identifiers
Aliases	H2BC9, H2B/j, H2BFJ, histone cluster 1, H2bh, histone cluster 1 H2B family member h, HIST1H2BH, H2B clustered histone 9
External IDs	OMIM: 602806; MGI: 3710645; HomoloGene: 134772; GeneCards: H2BC9; OMA:H2BC9 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	26,252,075 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	22,021,700 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; monocyte; ; jejunal mucosa; ; mucosa of transverse colon; ; right ventricle; ; thymus; ; bronchial epithelial cell; ; embryo; ; cartilage tissue; ; mucosa of sigmoid colon;
	Top expressed in
	granulocyte; ; embryo; ; genital tubercle; ; tail of embryo; ; bone marrow; ; zygote; ; Mesencephalon; ; esophagus; ; ileum; ; conceptus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein heterodimerization activity; protein binding; enzyme binding; ubiquitin-like protein ligase binding; STAT family protein binding;
Cellular component	chromosome; nucleosome; extracellular exosome; nucleus; nucleoplasm; cytosol; protein-containing complex;
Biological process	nucleosome assembly; protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	8345
	665622
	ENSG00000275713
	ENSMUSG00000069303
	Q93079
	P10853
	NM_003524
	NM_001110555; NM_001313878
	NP_003515
NP_835505; NP_001091448; NP_001300809; NP_001104025; NP_001300807;
	NP_835502; NP_835506; NP_835508
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H2B type 1-H is a protein that in humans is encoded by the HIST1H2BH gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.