H3F3B (gene)

H3-3B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4H9O, 5BNX, 3JVK, 5DWQ, 4L58, 4TMP, 5DX0, 4H9S, 4W5A, 3AV2, 3WTP, 4HGA, 4GUS, 4GY5, 3MUK, 3QLC, 4H9Q, 4N4I, 4GU0, 4GNE, 5BNV, 2L43, 3MUL, 4H9P, 3QLA, 4QQ4, 4GNF, 4U7T, 3ASK, 4O62, 4GNG, 4GUR, 4H9N, 4H9R, 3ASL, 3QL9, 5AY8, 5JA4
Identifiers
Aliases	H3-3B, H3.3B, H3 histone, family 3B (H3.3B), H3 histone family member 3B, H3.3 histone B, H3F3B, H3-3A, BRYLIB2
External IDs	OMIM: 601058; MGI: 1097686; HomoloGene: 134170; GeneCards: H3-3B; OMA:H3-3B - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	75,785,893 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	180,641,508 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; trigeminal ganglion; ; lactiferous duct; ; caput epididymis; ; lower lobe of lung; ; tail of epididymis; ; left testis; ; male germ cell; ; right testis;
	Top expressed in
	ganglionic eminence; ; neural tube; ; Mesencephalon; ; granulocyte; ; ventricular zone; ; thymus; ; lip; ; bone marrow; ; ileum; ; epiblast;
	More reference expression data
	n/a
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; histone binding; protein binding; protein heterodimerization activity; RNA polymerase II core promoter sequence-specific DNA binding; nucleosomal DNA binding;
Cellular component	nucleoplasm; chromosome; extracellular region; nuclear chromosome; extracellular exosome; Barr body; nucleosome; nucleus; protein-containing complex;
Biological process	telomere organization; epigenetic maintenance of chromatin in transcription-competent conformation; blood coagulation; positive regulation of cell growth; rDNA heterochromatin assembly; negative regulation of gene expression, epigenetic; male gonad development; multicellular organism growth; single fertilization; cell population proliferation; embryo implantation; negative regulation of chromosome condensation; spermatid development; nucleus organization; osteoblast differentiation; pericentric heterochromatin assembly; oogenesis; subtelomeric heterochromatin assembly; spermatogenesis; regulation of centromere complex assembly; muscle cell differentiation; nucleosome assembly; brain development; response to hormone; regulation of gene silencing by miRNA; regulation of megakaryocyte differentiation; regulation of hematopoietic stem cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	3021
	15078
	ENSG00000132475
	ENSMUSG00000060743
	P84243
	P84244
	NM_005324
	NM_008210
	NP_005315
	NP_032236; NP_032237
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H3.3 is a protein that in humans is encoded by the H3-3A, and the H3-3B genes.