3-hydroxyacyl-CoA dehydratase 2

HACD2
Identifiers
Aliases	HACD2, PTPLB, 3-hydroxyacyl-CoA dehydratase 2
External IDs	OMIM: 615939; MGI: 1918007; HomoloGene: 23409; GeneCards: HACD2; OMA:HACD2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	123,585,053 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	34,929,547 bp
RNA expression pattern
	Top expressed in
	gingival epithelium; ; external globus pallidus; ; vulva; ; jejunal mucosa; ; skin of thigh; ; skin of hip; ; endothelial cell; ; mucosa of colon; ; mucosa of sigmoid colon; ; human penis;
	Top expressed in
	right kidney; ; tail of embryo; ; lip; ; yolk sac; ; genital tubercle; ; zygote; ; esophagus; ; granulocyte; ; embryo; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein tyrosine phosphatase activity; enzyme binding; 3-hydroxyacyl-CoA dehydratase activity; protein binding; lyase activity; 3R-hydroxyacyl-CoA dehydratase activity; 3-hydroxy-behenoyl-CoA dehydratase activity; 3-hydroxy-lignoceroyl-CoA dehydratase activity; 3-hydroxy-arachidoyl-CoA dehydratase activity; very-long-chain 3-hydroxyacyl-CoA dehydratase activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; endoplasmic reticulum; membrane; integral component of endoplasmic reticulum membrane;
Biological process	fatty acid elongation; fatty acid biosynthetic process; sphingolipid biosynthetic process; long-chain fatty-acyl-CoA biosynthetic process; very long-chain fatty acid biosynthetic process; fatty acid metabolic process; lipid metabolism; peptidyl-tyrosine dephosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	201562
	70757
	ENSG00000206527
	ENSMUSG00000035376
	Q6Y1H2
	Q9D3B1
	NM_001329783; NM_001329784; NM_001329786; NM_001329787; NM_198402
	NM_023587
	NP_001316712; NP_001316713; NP_001316715; NP_001316716; NP_940684
	NP_076076
	Wikidata
View/Edit Human	View/Edit Mouse

3-hydroxyacyl-CoA dehydratase 2 is a protein that in humans is encoded by the HACD2 gene.