Hydroxyacyl-Coenzyme A dehydrogenase

HADH
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1F0Y, 1F12, 1F14, 1F17, 1IL0, 1LSJ, 1LSO, 1M75, 1M76, 2HDH, 3HAD, 3RQS
Identifiers
Aliases	HADH, HAD, HADH1, HADHSC, HCDH, HHF4, MSCHAD, SCHAD, Hydroxyacyl-Coenzyme A dehydrogenase, hydroxyacyl-CoA dehydrogenase
External IDs	OMIM: 601609; MGI: 96009; HomoloGene: 55888; GeneCards: HADH; OMA:HADH - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	108,035,241 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	131,065,750 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; right ventricle; ; Skeletal muscle tissue of rectus abdominis; ; mucosa of transverse colon; ; beta cell; ; thoracic diaphragm; ; kidney tubule; ; vastus lateralis muscle; ; body of tongue; ; myocardium of left ventricle;
	Top expressed in
	Paneth cell; ; condyle; ; medullary collecting duct; ; tunica adventitia of aorta; ; brown adipose tissue; ; cumulus cell; ; atrioventricular junction; ; fossa; ; migratory enteric neural crest cell; ; renal corpuscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	oxidoreductase activity; 3-hydroxyacyl-CoA dehydrogenase activity; NAD+ binding;
Cellular component	cytoplasm; mitochondrial matrix; mitochondrion; nucleoplasm;
Biological process	response to insulin; response to hormone; fatty acid beta-oxidation; negative regulation of insulin secretion; response to activity; fatty acid metabolic process; lipid metabolism; positive regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
Orthologs
	3033
	15107
	ENSG00000138796
	ENSMUSG00000027984
	Q16836
	Q61425
	NM_001184705; NM_005327; NM_001331027
	NM_008212
	NP_001171634; NP_001317956; NP_005318
	NP_032238
	Wikidata
View/Edit Human	View/Edit Mouse

Hydroxyacyl-Coenzyme A dehydrogenase (HADH) is an enzyme which in humans is encoded by the HADH gene.